8 Best Laundry Detergents For Urine Odor 2025, According to Experts

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Urine odor in clothes can be tough to remove. The right laundry detergent makes all the difference.

Urine smells can stick to fabrics and cause embarrassment. Ordinary detergents often fail to remove these odors fully. Using a detergent designed to fight urine smell helps keep clothes fresh and clean. These detergents break down odor-causing molecules and stop the smell from returning.

Choosing the best product saves time and effort in laundry. This guide highlights effective laundry detergents that target urine odor. You will learn which detergents work best for different fabrics and stains. Say goodbye to stubborn urine smells with the right detergent. Clean clothes. Fresh smells. Easy laundry days ahead.

Our Top Picks

1Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 ...
Top Pick

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 …

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2Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic ...
Best Quality

Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic …

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3Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder ...
Recommended

Pet Laundry Detergent Odor Remover – ACTIVE Enzyme Based Powder …

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4ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 ...

ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 …

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5Lysol Sport Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes ...

Lysol Sport Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes …

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6Febreze Laundry Detergent Additive for Pet Supplies, Maximum Strength In ...

Febreze Laundry Detergent Additive for Pet Supplies, Maximum Strength In …

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7LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner - ...

LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner – …

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8Zero Odor – Laundry Odor Eliminator - Permanently Eliminate laundry ...

Zero Odor – Laundry Odor Eliminator – Permanently Eliminate laundry …

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Top 8 Laundry Detergents For Urine Odor

Top Pick

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

1. Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

  • Brand: Nature’s Miracle
  • Manufacturer: Spectrum Brands Pet, LLC
  • Color: Multi
  • Dimensions: Weight: 2.0 pounds `

Transform your laundry routine with Nature’s Miracle Laundry Boost. This 32-ounce additive targets tough stains and odors effortlessly. Safe for all machines, it enhances your detergent’s power. The formula works wonders on stubborn spots, leaving clothes fresh. Perfect for pet owners and families alike. Enjoy cleaner, fresher laundry with every wash.

Advantages

  • Removes tough stains and odors effectively from clothes.
  • Works well with all types of washing machines.
  • Helps keep laundry fresh and clean longer.
  • Easy to use as an additive in every wash.
  • Safe for most fabrics and colors in your laundry.

Our Recommendations

This stain remover worked great on my kid’s sports clothes. Stains disappeared after just one wash. Tried it in my front-load washer with no problems. Clothes smelled fresh and clean every time. Easy to use. Just add it to the wash along with your detergent. No extra steps needed. My laundry looks brighter and smells much better now. I feel confident using it on all fabrics. Perfect for tough stains and bad odors. It saved my favorite shirt from the trash. A small bottle lasts a long time. A little goes a long way in every wash load.

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Best Quality

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

2. Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads

  • Brand: ACTIVE
  • Manufacturer: ACTIVE
  • Color: White
  • Dimensions: Weight: 2.0 Pounds `

This enzyme laundry booster removes tough stains like sweat, oil, and blood with ease. Its natural bio-active enzymes break down odors and grime gently yet effectively. Unscented and safe, it works well with any detergent for cleaner clothes. A 2-pound container provides 64 loads, making laundry fresh and odor-free longer. Perfect for those who want a simple, natural stain remover.

Advantages

  • Removes tough stains like sweat, oil, and blood effectively.
  • Keeps clothes fresh by eliminating bad odors naturally.
  • Works well with detergent to boost cleaning power.
  • Uses natural enzymes that break down stains safely.
  • Covers up to 64 loads, making it long-lasting.

Our Recommendations

This enzyme laundry booster works well to remove tough stains like sweat, oil, and blood. Clothes come out fresh without any strong smell. It mixes easily with detergent and cleans deeply. The powder lasts a long time—about 64 loads. Natural enzymes break down stains quickly and help get rid of odors. Perfect for those who want a gentle, effective laundry additive. No harsh chemicals, just clean clothes every time. Great value for a big 2-pound container. Washing feels easier and results are always good.

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Recommended

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

3. Pet Laundry Detergent Odor Remover – ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator – 64 Loads

  • Brand: ACTIVE
  • Manufacturer: ACTIVE
  • Color: White
  • Dimensions: Weight: 2.0 pounds `

This pet laundry detergent removes tough odors like cat pee and dog drool easily. Its active enzymes break down stains and smells naturally. Safe for use in HE washers, it cleans pet beds and clothes gently. You get 64 loads, making it a great choice for regular pet laundry. Keeps your home fresh and your pet’s items clean every time.

Advantages

  • Effectively removes tough pet stains like urine and drool.
  • Keeps dog beds and fabrics fresh with natural enzymes.
  • Safe for HE washers and gentle on all fabrics.
  • Eliminates strong odors, leaving a clean, pleasant scent.
  • Covers 64 loads, providing long-lasting cleaning power.

Our Recommendations

This detergent removed tough dog smells from my laundry fast. The powder works well in my HE washer. Stains and odors faded after just one wash. My pet’s bed smells fresh and clean now. Easy to use and gentle on fabrics too. I like that it uses natural enzymes to fight odors. Great value with 64 loads in one box. Perfect for homes with dogs and cats. Keeps clothes and bedding smelling nice every time. Definitely a good choice for pet owners.

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ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 Loads Liquid Laundry Detergent, 166.5 Fl oz

4. ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 Loads Liquid Laundry Detergent, 166.5 Fl oz

  • Brand: Arm & Hammer
  • Manufacturer: Church & Dwight
  • Dimensions: Weight: 10.40625 Pounds `

Experience fresh, clean clothes with ARM & HAMMER Plus OxiClean Odor Blasters. This liquid detergent fights tough odors and stains in every load. The Fresh Burst scent keeps laundry smelling great for days. Perfect for families, it handles 128 loads with one large bottle. Easy to use and gentle on fabrics, it delivers reliable cleaning power.

Advantages

  • Powerful stain removal keeps clothes looking fresh and clean. Tackles tough stains easily.
  • Odor-fighting formula leaves laundry smelling great. Eliminates unpleasant odors effectively.
  • Large bottle provides value. Offers up to 128 loads per purchase.
  • Safe for all machines. Compatible with both standard and HE washers.
  • Easy-to-use liquid detergent pours smoothly. Reduces mess during laundry tasks.

Our Recommendations

This detergent cleans clothes very well and removes tough stains easily. Clothes smell fresh for days. The scent is not too strong, just right. One bottle lasts a long time because it covers many loads. Clothes feel soft and look bright after washing. It works great in both hot and cold water. I noticed no skin irritation, even with sensitive skin. The liquid is easy to pour and does not spill. Using this detergent saves money since you need less per wash. Overall, it makes laundry simple and effective every time.

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Lysol Sport Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and Activewear, Eliminates Odor Causing Bacteria, 90oz

5. Lysol Sport Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and Activewear, Eliminates Odor Causing Bacteria, 90oz

  • Brand: Lysol
  • Manufacturer: AmazonUs/RECAS
  • Dimensions: Height: 11.3 inches Width: 7.5 inches Length: 4.6 inches Weight: 5.625 Pounds `
  • Publication Date: 2019-11-15T00:00:01Z

Perfect for gym clothes and activewear, Lysol Sport Laundry Sanitizer Additive kills odor-causing bacteria. It keeps your workout gear fresh and clean after every wash. Safe to use with your regular detergent, this sanitizing liquid helps remove tough smells. Long-lasting freshness makes your sportswear more pleasant to wear. A simple way to fight bacteria and keep your clothes smelling great.

Advantages

  • Kills bacteria that cause bad odors in gym clothes.
  • Keeps activewear fresh and clean after every wash.
  • Works well with regular detergent for extra protection.
  • Safe for all types of sports fabrics and colors.
  • Large 90oz bottle lasts through many laundry loads.

Our Recommendations

This Lysol Sport Laundry Sanitizer works great on my gym clothes. It removes bad smells quickly and keeps clothes fresh. I add it to my wash, and it kills odor-causing bacteria well. Clothes feel clean and smell nice after every wash. Perfect for activewear that needs extra care. The 90oz bottle lasts a long time, so I don’t need to buy often. Easy to use and fits right into my laundry routine. A simple way to keep sports clothes clean and fresh.

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Febreze Laundry Detergent Additive for Pet Supplies, Maximum Strength In Wash Pet Odor Eliminator, Designed to Remove Tough Odors in Fabrics and Clothing in a Single Wash, Fresh Scent, 98 fl oz

6. Febreze Laundry Detergent Additive for Pet Supplies, Maximum Strength In Wash Pet Odor Eliminator, Designed to Remove Tough Odors in Fabrics and Clothing in a Single Wash, Fresh Scent, 98 fl oz

  • Brand: Febreze
  • Manufacturer: AmazonUs/NEHAD
  • Color: No Color
  • Dimensions: Height: 7.59 inches Width: 4.5 inches Length: 11.25 inches Weight: 7.0 pounds `
  • Publication Date: 2020-02-28T00:00:01Z

Febreze Laundry Detergent Additive removes strong pet odors from clothes and fabrics in just one wash. Tough smells disappear, leaving a fresh, clean scent behind. Perfect for homes with pets, it works well with your regular detergent. Easy to use and highly effective, it keeps laundry smelling great every time. Freshness lasts longer, making your clothes and fabrics feel clean and comfortable.

Advantages

  • Eliminates strong pet odors from clothes and fabrics easily.
  • Works effectively in just one wash cycle.
  • Leaves a fresh, clean scent on laundry.
  • Safe and gentle for use with pet supplies.
  • Large 98 fl oz size lasts through many washes.

Our Recommendations

This Febreze Laundry Detergent Additive really works well on pet smells. Clothes come out smelling fresh and clean every time. Tough odors disappear in just one wash. Fabrics feel soft and smell great afterward. Perfect for homes with pets. Easy to use and lasts a long time. Makes laundry day much better and fresher. Definitely a good choice for pet owners.

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LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner - 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet

7. LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner – 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet

  • Brand: ATP
  • Manufacturer: Alpha Tech Pet, Inc
  • Dimensions: Height: 9.5 inches Width: 6.0 inches Length: 3.0 inches Weight: 4.0 pounds `

LaundraPet 3X Strength Premium Laundry Detergent cleans tough pet stains and odors with ease. Its enzyme formula breaks down protein-based messes for deep cleaning. Safe for all fabrics, it keeps clothes fresh and soft after every wash. One bottle lasts for 96 washes, offering great value. Perfect for homes with pets, it helps maintain a clean and odor-free environment.

Advantages

  • Removes tough pet stains and odors deeply and effectively.
  • Enzyme cleaner breaks down proteins for better stain removal.
  • Works well on various fabrics without causing damage.
  • Provides 96 washes, making it cost-efficient and long-lasting.
  • Safe for use around pets and family members.

Our Recommendations

LaundraPet 3X Strength detergent cleans pet stains very well. It removes odors quickly and leaves clothes fresh. The enzyme formula works fast on tough spots. A little detergent goes a long way, so the bottle lasts. Clothes come out soft and smell clean after washing. Easy to use and great for pet owners. Strong enough for big messes but gentle on fabric. Definitely helps keep laundry smelling good and looking fresh.

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Zero Odor – Laundry Odor Eliminator - Permanently Eliminate laundry Odor – Patented Molecular Technology Best For Clothes, Towels & Linens, Shoes, Bags, Etc. - rinse and refresh Again, 16oz

8. Zero Odor – Laundry Odor Eliminator – Permanently Eliminate laundry Odor – Patented Molecular Technology Best For Clothes, Towels & Linens, Shoes, Bags, Etc. – rinse and refresh Again, 16oz

  • Brand: Zero Odor
  • Manufacturer: Zero Odor
  • Color: White
  • Dimensions: Height: 9.0 inches Width: 2.0 inches Length: 4.0 inches Weight: 1.2 pounds `

Zero Odor Laundry Odor Eliminator removes stubborn smells from clothes, towels, and linens. Its patented molecular technology works deep to stop odors forever. Safe for use on shoes, bags, and other washable items. Just add during rinse to refresh fabrics without harsh chemicals. Keeps laundry smelling clean and fresh every time. Perfect for families wanting a simple, effective odor solution.

Advantages

  • Eliminates strong odors from clothes, towels, and linens completely.
  • Uses patented molecular technology for long-lasting freshness.
  • Safe for shoes, bags, and other washable items.
  • Works quickly to remove smells without harsh chemicals.
  • Refreshes laundry with just one easy rinse.

Our Recommendations

Zero Odor Laundry Odor Eliminator works wonders. Clothes smell fresh after just one wash. No lingering odors at all. Patented Molecular Technology truly sets it apart. Even the toughest smells vanish. Towels and linens feel refreshed. Shoes and bags also benefit. Zero Odor leaves them smelling clean. A great find for households. Easy to use. Just add to the wash. Noticeable difference with every load. Highly recommend for anyone tired of persistent odors. A reliable solution for all laundry needs.

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Frequently Asked Questions

What Makes A Laundry Detergent Good For Urine Odor Removal?

A good detergent has enzymes that break down urine molecules and remove smells effectively.

Can Regular Detergents Remove Urine Odor From Clothes?

Regular detergents may clean clothes but often don’t fully eliminate urine smells.

How To Use Laundry Detergent To Remove Urine Odor Best?

Use hot water and enough detergent, then add a second wash if needed.

Are Enzyme-based Detergents Better For Urine Odor Than Others?

Yes, enzyme detergents target and break down urine proteins, removing odors deeply.

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Buying Guide On Best Laundry Detergents For Urine Odor

1. Check for Odor-Eliminating Ingredients

Choose detergents with enzymes or baking soda. These break down urine molecules and remove smells.

2. Pick a Detergent Suitable for Fabric Type

Some detergents work better on cotton, others on synthetics. Read labels carefully for fabric care.

3. Consider Detergent Form: Liquid, Powder, or Pods

Liquid detergents dissolve quickly and target stains well. Powders may be cheaper but take longer to dissolve. Pods offer convenience and pre-measured doses.

4. Look for Hypoallergenic Options

Detergents with no dyes or perfumes reduce skin irritation. Ideal for sensitive skin or babies’ clothes.

5. Review Washing Machine Compatibility

High-efficiency (HE) machines require low-sudsing detergents. Standard machines work with most detergent types.

6. Evaluate Cleaning Power on Stains

Choose detergents that mention stain removal. Urine stains need strong cleaning agents to disappear fully.

7. Check Customer Reviews for Effectiveness

Read feedback to see if the detergent removes urine odor well. Real user experiences help make good choices.

8. Compare Price and Quantity

Balance cost with how much detergent you get. Bigger bottles may save money but check expiration dates.

9. Consider Eco-Friendly Formulations

Biodegradable detergents protect the environment. Look for labels saying “green” or “eco-friendly.”

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10. Test with a Small Load First

Try the detergent on a small wash. This confirms it removes odor without damaging fabric.

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Conclusion

Choosing the right laundry detergent makes a big difference in removing urine odor. Strong detergents with enzymes work best to break down stains. Some detergents also add fresh scents to keep clothes smelling clean longer. Always follow the washing instructions on your clothes for the best results.

Using the right amount of detergent helps avoid leftover smells. Washing clothes quickly after accidents stops odors from settling. Remember, not all detergents work the same, so find one that suits your needs. Clean clothes mean a fresher home and more comfort.

With the right detergent, urine odors will not be a problem anymore. Keep your laundry routine simple and effective. Your clothes will look and smell great every time. A good detergent saves time and effort. It’s worth trying a few options to see what works best for you.

Clean laundry brings peace of mind.